Phytochemical constituents and biological properties of Scutellaria condensata subsp. pycnotricha

Authors

  • Dara Dastan Department of Pharmacognosy, School of Pharmacy, Medicinal Plants and Natural Products Research Center, Hamadan University of Medical Sciences, Hamadan, Iran
  • Farhad Ismail Ahmadi Department of Biology, College of Education, University of Garmian, Kurdistan Region of Iraq
  • Rohollah Fathollahi Department of Pharmacognosy, School of Pharmacy, Medicinal Plants and Natural Products Research Center, Hamadan University of Medical Sciences, Hamadan, Iran
Abstract:

Scutellaria is widely used in traditional medicine as a medical plant, in Asian countries, especially in China. It has been applied in treatment because of its sedative, antithrombotic, anti-inflammatory, antioxidant, and antiviral effects. Scutellaria condensata Rech. f. subsp. pycnotricha (Rech. f.) Rech. f. is a wild perennial plant which  grows in Iran. In this study, GC-FID and GC-MS were used to examine the hydro-distilled volatile oil from the aerial parts of S. condensate. The total phenolic and flavonoids contents were determined by spectrophotometer. Also, the evaluation of antioxidant activity of essential oil and the methanolic extract was carried out using DPPH assay. The antibacterial activity of S. condensate essential oil was examined against four Gram-negative and five Gram-positive bacteria. Additionally, the review evaluation of volatile oil compounds of Scutellaria species was done. The process led to the identification of thirty-two compounds constituting 96.5% of the volatile oil. The major constituents were found to be linalool (25.3%), carvacrol (16.3%), and (E)-caryphyllene (13.4%). As a result, the highest scavenging activity belonged to methanolic extract (IC50= 38.2 µg/ml), followed by essential oil (IC50= 93.2 µg/ml). The total phenolic and flavonoid content were (120.7 mg GAE/g sample) and (78.6 mg QE /g sample), respectively for the methanolic extract. The essential oil showed moderate to high inhibitory activity against the Bacillus cereus, Escherichia coli, Staphylococcus epidermidis and Bacillus pumilus. The study indicates S. condensate potential for being a prospective antioxidant and antibacterial source in pharmaceutical and food industries.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

Biological Activity and Phytochemical Study of Scutellaria platystegia

This study aimed to determine biological activity and phytochemical study of Scutellaria platystegia (family Labiatae). Methanolic (MeOH) extract of aerial parts of S. platystegia and SPE fractions of methanolic extract (specially 20% and 40% methanolic fractions), growing in East-Azarbaijan province of Iran were found to have radical scavenging activity by DPPH (2, 2-diphenyl -1- pycryl hydraz...

full text

Biological Activity and Phytochemical Study of Scutellaria platystegia

This study aimed to determine biological activity and phytochemical study of Scutellaria platystegia (family Labiatae). Methanolic (MeOH) extract of aerial parts of S. platystegia and SPE fractions of methanolic extract (specially 20% and 40% methanolic fractions), growing in East-Azarbaijan province of Iran were found to have radical scavenging activity by DPPH (2, 2-diphenyl -1- pycryl hydraz...

full text

Phytochemical Constituents and Biological Activities of Salvia suffruticosa

Background and objectives: Salvia suffruticosa is a perennial plant from Lamiaceae family. Many Salvia species have been employed as medicinal plants; despite the medicinal potentials of S. suffruticosa, there is limited studies regarding its phytochemical profile or biological properties. The aim of the present study was to investigate the chemical c...

full text

Biological Activity and Phytochemical Study of Scutellaria platystegia

This study aimed to determine biological activity and phytochemical study of Scutellaria platystegia (family Labiatae). Methanolic (MeOH) extract of aerial parts of S. platystegia and SPE fractions of methanolic extract (specially 20% and 40% methanolic fractions), growing in East-Azarbaijan province of Iran were found to have radical scavenging activity by DPPH (2, 2-diphenyl -1- pycryl hydraz...

full text

biological activity and phytochemical study of scutellaria platystegia

this study aimed to determine biological activity and phytochemical study of scutellaria platystegia (family labiatae). methanolic (meoh) extract of aerial parts of s. platystegia and spe fractions of methanolic extract (specially 20% and 40% methanolic fractions), growing in east-azarbaijan province of iran were found to have radical scavenging activity by dpph (2, 2-diphenyl -1- pycryl hydraz...

full text

Phytochemical Constituents and Biological Activities of Homalium Zeylanicum Benth

Homalium zeylanicum is a rare and phytochemically less explored tropical tree. Chemical examination of bark and leaf of this species yielded phenolic compounds 3Phenyl coumarin (1) and 4'-O-Methyl-Epigallo catechin (2). The structures of the compounds were established on the basis of various NMR spectral data. The extracts of bark, leaf and their isolated compounds showed both antioxidant and a...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 8  issue 3

pages  201- 211

publication date 2020-07-01

By following a journal you will be notified via email when a new issue of this journal is published.

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023